Recommended Performance Standards
for In Vitro Test Methods
for Skin Corrosion

Interagency Coordinating Committee on the
Validation of Alternative Methods (ICCVAM)
and the
National Toxicology Program (NTP) Interagency Center for
the Evaluation of Alternative Toxicological Methods (NICEATM)
National Institute of Environmental Health Sciences
National Institutes of Health
U.S. Public Health Service
Department of Health and Human Services


PDF [5.6 MB] NIH Publication No: 04-4510



Table of Contents

ICCVAM - NICEATM Overview
Table of Contents [printable PDF file]
List of Tables
List of Abbreviations and Acronyms
ICCVAM Representatives
Acknowledgements
Preface
Executive Summary

1.0 Purpose and Background of Performance Standards

  1. Introduction
  2. Elements of ICCVAM Performance Standards
  3. ICCVAM Process for the Development of Performance Standards
  4. ICCVAM Development of Recommended Performance Standards for In Vitro Test Methods for Skin Corrosion

2.0 In Vitro Membrane Barrier Test Systems for Skin Corrosion

  1. Background
  2. Principles of In Vitro Membrane Barrier Test Systems for Skin Corrosion
  3. Essential Test Method Components
  4. Reference Chemicals
  5. Accuracy and Reliability

3.0 In Vitro Human Skin Model Systems for Skin Corrosion

  1. Background
  2. Principles of In Vitro Human Skin Model Systems for Skin Corrosion
  3. Essential Test Method Components
  4. Reference Chemicals
  5. Accuracy and Reliability

4.0 In Vitro Skin Transcutaneous Electrical Resistance (TER) Test for Skin Corrosion

  1. Minimum Procedural Standards
  2. Principles of the In Vitro Skin TER Test for Skin Corrosion
  3. Essential Test Method Components
  4. Reference Chemicals
  5. Accuracy and Reliability

5.0 References

Appendices




This page was last updated May 27, 2004