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Appendix A, Page 1 of 2:
The following list of chemicals includes information from Appendix B, Table 1 of the original submission (Appendix C), unpublished data from a laboratory participating in the validation studies, and supplemental sources. Participating laboratories in the validation studies have provided statements indicating that the studies were conducted under Good Laboratory Practice (GLP) guidelines or within the spirit of GLP. The laboratory that submitted unpublished data also provided a representative sample of raw data for review. NICEATM concluded that the data provided supported the results given in the original submission (Appendix C). NICEATM has included human patch test allergen information from the Contact Dermatitis web site (Truett, 1998); chemical class assignments (some of which are based on categories used by Ashby et al., 1995); product class information from The Merck Index, 12th edition (Budavari, 1996), and other sources; dermal irritancy potential; sensitization incidence in a cohort of patch tested dermatitis patients (from Marzulli and Maibach, 1996) [Dermatotoxicology]); and other comments. |
