Presentations for Workshop on Best Practices for Assessing the Potential for Chemically
Induced Eye Injuries
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Please note:
- The video files and some of the presentations are large files that may take several minutes to
download or open, depending on your connection speed.
- Some of the presentations may vary slightly in appearance from those presented
at the workshop. However, no content has been changed.
Introduction and Public Health Impact of Chemically Induced Eye Injuries
[PDF]
RADM William Stokes, DVM, U.S. Public Health Service, NICEATM, NIEHS
Review of Alternative Test Methods and Integrated Strategies for Ocular Safety Assessments
[PDF]
Jill Merrill, PhD, Center for Drug Evaluation and Research, FDA
Study Director and IACUC Responsibilities: Consideration of Available Reduction, Refinement,
and Replacement Alternative Test Methods (USDA)
[PDF]
Jodie Kulpa-Eddy, DVM, Animal and Plant Health Inspection Service, Department of Agriculture
Current Guidelines for Ocular Safety Testing
[PDF]
Deborah McCall, Office of Pesticide Programs, EPA
ICCVAM Evaluation and Recommendations on Best Practices for Incorporating Pain Management and Humane Endpoints in Ocular Safety Testing
[PDF]
RADM William Stokes, DVM, U.S. Public Health Service, NICEATM, NIEHS
The Bovine Corneal Opacity and Permeability (BCOP) Test Method: Validation Status
[PDF]
Elizabeth Lipscomb, PhD, ILS, Inc., Contractor Supporting NICEATM
Conducting and Interpreting the BCOP Test Method
[PDF]
Hans Raabe, Institute for In Vitro Sciences, Inc.
The Isolated Chicken Eye Test Method:
Validation Status/Conducting and Interpreting the Method
[PDF]
David Allen, PhD, ILS, Inc., Contractor Supporting NICEATM
View video on application of liquid test substance to accompany slide 13 [AVI]
View video on application of solid test substance to accompany slide 13 [AVI]
Captioned and narrated versions of videos available on archived webcast
 : begin at 163 minutes
The Cytosensor Microphysiometer (CM) Test Method: Validation Status
[PDF]
Elizabeth Lipscomb, PhD, ILS, Inc., Contractor Supporting NICEATM
Conducting and Interpreting the CM Test Method
[PDF]
Rodger Curren, PhD, Institute for In Vitro Sciences, Inc.
Roundtable Discussion:
Regulatory Agency Requirements and Acceptable Alternative Test Methods for ACD Hazard Assessments
- Consumer Product Safety Commission
Joanna Matheson, PhD
- Environmental Protection Agency
Jack Fowle, PhD
- Food and Drug Administration
Suzanne Fitzpatrick, PhD
- Occupational Safety and Health Administration [PDF]
Surender Ahir, PhD
Alternative Test Methods for ACD Hazard Assessment: Case Studies in Breakout Groups
View case study presentations and discussion summaries [PDF]
New Models in the Validation Pipeline for ACD Hazard Testing
- Jill Merrill, PhD, Center for Drug Evaluation and Research, FDA [PDF]
- Hitoshi Sakaguchi, PhD, Kao Corporation [PDF]
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