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EPISKINTM, EpiDermTM(EPI-200) and the Rat Skin Transcutaneous

Electrical Resistance (TER) Assay
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Overview and Performance Standards

ICCVAM evaluated and recommended four validated test methods for assessing the dermal corrosivity hazard potential of chemicals: Corrositex®, EPISKIN™, EpiDerm™ (EPI-200), and the rat skin transcutaneous electrical resistance (TER) assay. At the request of the U.S. EPA, ICCVAM established performance standards for the three proprietary dermal corrosivity test methods (Corrositex®, EPISKIN™, EpiDerm™ [EPI-200]) and the nonproprietary rat skin TER test method.

Recommended Performance Standards for In Vitro Test Methods for Skin Corrosion
(NIH Publication 04-4510, May 2004)

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ICCVAM Dermal Corrosivity and Irritation Working Group (DCIWG) Proposed Minimum Performance Standards (MPS) for three types of In Vitro Tests for Skin Corrosion (June 2003):
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